MFN2 antibody

Catalog No. ABIN7268606

The Rabbit Monoclonal anti-MFN2 antibody has been validated for WB. It is suitable to detect MFN2 in samples from Human.

Quick Overview for MFN2 antibody (ABIN7268606)

Target: MFN2 (Mitofusin 2 (MFN2))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This MFN2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MFN2 Antibody

Purpose: Mitofusin 2 Rabbit mAb

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Monoclonal Antibodies

Purification: Affinity purification

Immunogen: A synthesized peptide derived from human Mitofusin 2.

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for MFN2

Target: MFN2 (Mitofusin 2 (MFN2))

Alternative Name: MFN2

Background: This gene encodes a mitochondrial membrane protein that participates in mitochondrial fusion and contributes to the maintenance and operation of the mitochondrial network. This protein is involved in the regulation of vascular smooth muscle cell proliferation, and it may play a role in the pathophysiology of obesity. Mutations in this gene cause Charcot-Marie-Tooth disease type 2A2, and hereditary motor and sensory neuropathy VI, which are both disorders of the peripheral nervous system. Defects in this gene have also been associated with early-onset stroke. Two transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008],CMT2A,CMT2A2,CMT2A2A,CMT2A2B,CPRP1,HMSN6A,HSG,MARF,MFN2,Mitofusin 2,Apoptosis,Autophagy,Autophagy_Mitochondrial Control of Autophagy,Cancer,Cell Biology & Developmental Biology,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial metabolism_Mitochondrial markers,Mitochondrial metabolism_Mitophagy fission and fusion,Neurodegenerative Diseases,Neuroscience,Signal Transduction,MFN2

Molecular Weight: 80kDa

Gene ID: 9927

UniProt: O95140

Pathways: Skeletal Muscle Fiber Development